Karsa · HRAM-MS com MPCI

Orbion: high resolution to understand air chemistry

An integrated system of multipressure chemical ionization and high resolution mass spectrometry and exact mass, developed to separate nearby species, assign molecular formulas and track complex atmospheric chemistry in real time.

up to 240.000resolution power in m/z 200
1 ppm RMSlock mass accuracy
sub-pptvreported detection limits
Mass spectrometer Karsa Orbion with integrated system, monitor and sample counter
A system, from lab to fieldIntegrated architecture, automated cycles and solid reagents.
Main capacities

High-resolution molecular characterization across a broad chemical range

Orbion combines isobaric species separation, ultratrace sensitivity, ionization exchange, and a data flow prepared for scientific research.

m/z

High resolution and exact mass

Resolution from 120,000 to 250,000, according to the model, to reveal previously overlapping signs and restrict elemental compositions.

MPCI

Multipressure coverage

The automatic cycle between reagent ions expands the observation of VOCs, acids, amines and oxidation products.

pptv

Reactive species in ultratrace

Sub-pptv detection limits reported by the manufacturer to accompany reactive compounds in low concentration.

24/7

Integrated operation

Automation of routines, solid reagents and components assembled in a single system for continuous and unaccompanied operation.

How the analysis happens

From gas sample to molecular identity

The flow unites chemical coverage, high resolution separation and organized data processing, without depending on a simplified reading of nominal mass.

1

Sample introduction

The gaseous composition of the environment, experiment or campaign is conducted to the integrated system.

2

MPCI Ionization

The automatic exchange between NO3−, Ur+ and fluoranthene+ expands the classes of observed compounds.

3

HRAM Analysis

The analyzer separates masses very close and provides accuracy to support formula assignments.

4

Data processing in Mascope

Ingestion, visualization, quality control and analysis are organized in a collaborative environment.

Close example of m/z 309 showing isobaric species solved in high resolution
Why the resolution matters: in the example of the manufacturer near m/z 309, indistinguishable species in 10,000–20,000 appear separated from 120,000.
Applications

Where Orbion supports atmospheric research

Simultaneous coverage of different chemical classes is especially useful when primary emissions, reactions and secondary products need to be interpreted as the same process.

ATM

Air chemistry

Characterization of reactive species, oxidation products and chemical transformations in complex mixtures of air.

VOC

Volatile and biogenic emissions

Monitoring of newly emitted volatile hydrocarbons and subsequent formation of oxidised products.

AIR

Internal air quality

Comparison of composition before, during and after events that alter the chemistry of internal environments.

OOM

Highly oxygenated acids, amines and molecules

Research of classes with distinct chemical properties, including HOMs/OOMs, with complementary ionization cycles.

Internal air mass defect chart before peeling an orange
AInternal-air spectrum before the event.
Internal air mass defect chart after peeling an orange
BAfter peeling an orange, emissions and secondary products appear.

Documented example: in the orange peel experiment, Orbion recorded the chemical cascade from fresh emissions of volatile hydrocarbons to secondary products using a single instrument.

Orbion family

Three resolution levels, two options with MS/MS

The choice depends on the required separation and the need for MS/MS experiments. The other conditions of the application must be confirmed in the final configuration.

FeatureOrbion 120Orbion 180Orbion 240
Resolution power
ΔM/M em m/z 200
Up to 120,000Up to 180,000Up to 240.000
MS/MS CapacitySimNo, no, no.Sim
Polarity/reagent switchingUp to 1.4 Hz; 0,1 Global Hz
Mass accuracy1 ppm RMS com lock mass

Values reproduced in the catalogue Orbion rev. 251017. See the full specification for test conditions, configuration and performance details.

Data preview of the orange experiment on the Mascope platform
Organisation

Mascope: data processing and reproducible workflows

Mascope is the collaborative platform and open source integrated with Orbion to automate atmospheric data intake, processing and visualization.

Browser viewsQuick inspection, target analysis and quality control by batch and file.
Shared workspacesCollaborative organization of measurements, processing and results.
JupyterLab, Python e APIExtensible flows to adapt data processing to the scientific question.
Field Ready

Integration for laboratory and field operation

Orbion brings its components together in a validated system and is designed for reliability, quick configuration and continuous operation. This is a transportable platform for campaigns, not a portable hand analyzer.

60 minconfiguration time informed
12 hup to the first informed measurements
Transit caseoption for system transport
Solid reagentsno hazardous chemicals in the described routine
Karsa Orbion system being moved during deployment at a research facility
Technical specifications

Infrastructure and operating conditions

The requirements below help to evaluate deployment. The final configuration must be validated with SENS for the selected application, location and model.

System and performance

ArchitectureMPCI + HRAM analyzer + Mascope platform
Resolution120,000–250,000, according to the model, in m/z 200
Mass accuracy1 ppm RMS com lock mass
Detection limitsSub-pptv as reported by the manufacturer
CoverageVOCs, amines, acids and HOMs/OOMs

Installation

DimensionsA 1400 × L 730 × C 1240 mm without pump
Peso280 kg without the pump
Power3000 W for the complete system
Temperature18–27 °C; maximum variation of 0,5 °C/min
Humidity20–80%, no condensation

Gases

HP Nitrogen99%; 35 Ln/min
Nitrogen UHP99,999%; 0,03 Ln/min
GenerationThe two supplies can be supplied by a single nitrogen generator

Operation and transport

Mode switchingAutomated in seconds
TransportTransit case available
Settings60 minutes, according to catalogue
First measurements12 hours according to catalogue

Technical source: Orbion Brochure A4, revision 251017, Karsa (2025). Values and compatibility shall be confirmed in the technical proposal and in the complete specification in force.

Technical materials

Karsa Orbion Catalog

The official document is embedded in this HTML file and can be downloaded even when the page is opened offline.

PDF
Orbion — High Resolution Multi-Pressure Chemical Ionization Mass SpectrometerOfficial catalogue · Karsa · rev. 251017 · 4 pages
Frequently Asked Questions

Questions about Orbion

What does Karsa Orbion measure?

Orbion was developed to detect a wide range of compounds in the gaseous phase, including VOCs, amines, acids, HOMs/OOMs and oxidation products in studies of atmospheric chemistry and internal air.

What is MPCI in Orbion?

MPCI is the chemical multipressure ionization. In Orbion, the automatic cycle between reactive ions expands chemical coverage and allows observing distinct classes of compounds with a single integrated system.

What's Orbion's resolution?

The family offers up to 120,000 in Orbion 120, up to 180,000 in Orbion 180 and up to 250,000 in Orbion 240, with the reference value reported in m/z 200.

What models do MS/MS offer?

According to the catalogue, Orbion 120 and Orbion 240 offer MS/MS capacity; Orbion 180 does not offer this feature.

Can Orbion be used in field campaigns?

The manufacturer presents Orbion as field ready. The integrated system can be transported in transit case, with a stated setup time of 60 minutes and first measurements within 12 hours. The equipment is not handheld and weighs 280 kg without the pump.

How are Orbion data analyzed?

Orbion integrates Mascope, collaborative platform and open source for ingestion, processing, viewing, quality control and extensible flows in Python, API, and JupiterLab.

Assessment of Orbion for its application

Talk to SENS about species of interest, measuring environment, resolution, MS/MS and installation infrastructure.

Talk to a specialist